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American car manufacturers are seeing 30-40% volume loss and even though jetsetting auto execs might be getting their just desserts (or, looking at some of their salaries, are just getting dessert), the millions of mechanics, parts dealers, salesmen, and factory workers -- not to mention the job loss of collateral industries -- are just getting screwed.
ptrn-1 animals also often exhibit loss of collateral branch and associated presynaptic structures.
(B ) ptrn-1 (js1286 ) animals showing PLM neurite overextensions, ectopic synaptic varicosities, loss of collateral branches and associated PLM synaptic varicosities, and secondary posterior-directed ALM processes (double arrows) are noted.
Defects seen in PLM neurons included loss of collateral branches and presynaptic varicosities, as well as overextended neurites that exited the lateral cord and formed ectopic presynaptic varicosities in the ventral nerve cord anterior to the vulva.
That P-gp is necessary is evidenced by the loss of collateral sensitivity in the presence of specific efflux inhibitors or upon genetic silencing of the transporter; that P-gp is sufficient is demonstrated by the finding that the P-gp-potentiated toxicity of these MDR-selective compounds persists in several cell lines with intrinsic or acquired MDR.
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In the most striking example to emerge from studies of this type, two groups [ 26, 27] reasoned that cells defective for homologous recombination should be hypersensitive to loss of alternative, collateral DNA repair pathways, such as the base-excision repair pathway.
One can expect that lesion of intrahippocampal administration of kainate would produce not only cell death in CA3 area, and loss of Schaffer collaterals, but also change the firing mode of surviving neurons and generally increase their excitability [62].
21 This hypothesis considers critical irrigation to the foot, whereby medium-sized "patchy atherosclerosis" is associated with acute septic thrombosis and loss of small collaterals with surrounding inflammation.
"There's a lot of collateral damage".
Civilian loss of life as "collateral damage" can be lawful only if it is proportionate to the military objective.
There are virtually no places left in UN schools used as shelters in Gaza City, forcing families who have fled from their homes to sleep in tents or out in the open, bringing with it the chances of massive loss of lives in collateral damage.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com