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The response to cell-extrinsic DNA damage characterized in vitro is recapitulated in vivo in DCIS lesions, which exhibit telomere loss, heightened DNA damage response, and increased activin A and cyclooxygenase-2 expression.
Previous research determined that widowhood promotes anxiety and depression by increasing concerns about living alone and loneliness [ 27], job loss heightened a two- to three- fold rate of anxiety and depression by increasing financial strain and heightening reactivity to stress [ 27, 28].
These events in epithelial cells in vitro, including telomere loss, heightened DNA damage response, and activin A expression, are observed in breast ductal carcinoma in situ lesions surrounded by stroma bearing hallmarks of activated fibroblasts and immune and endothelial cell infiltration.
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This result suggests that ALS is characterized by genuine functional alterations (metabolic, chemical or molecular) on top of the neuronal loss, heightening the functional consequences of local GM atrophy.
Declines in its other businesses and BOA's allotment of $13.4 billion for credit losses heightened concern among investors.
In the case of those respondents who were describing emotions about a pregnancy after prior loss, evidence suggests that 'pregnancies following perinatal loss involve heightened anxiety relative to first pregnancies' (Geller et al., 2004: 40) and a risk that a subsequent loss may be higher (Cramer and Wise, 2000).
While not without faults, stop-loss orders can be a very simple strategy to use when sensitivity to loss is heightened.
They were booed by home fans at half-time in their 3-1 defeat by Aston Villa, a loss which heightened their relegation fears.
The initial symptoms are typically insidious, consisting of irritability, impulsivity, aggression, depression, short-term memory loss and heightened suicidality.
McKee et al. recently described the "spectrum of disease" in CTE: "CTE is clinically associated with symptoms of irritability, impulsivity, aggression, depression, short-term memory loss and heightened suicidality" [ 5].
The importance of having a good hair care regime to prevent hair loss is heightened by being in a hard water area.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com