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We previously reported that general conditions, symptoms onset and motor performance were worsened in SOD1-G93A mice lacking P2X7, with spinal cord gliosis and neuronal loss augmented.
Yin and colleagues independently generated a Grn knockout mouse model from which they discovered that Pgrn loss augmented inflammation, leading to an increase in the production of proinflammatory cytokines [ 71].
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WT p53 and NF- κB antagonize each other's activities, and thus it is not surprising that p53 loss augments NF- κB activity.
It is evident that in this case the excitation and energy loss has augmented in the same proportion because the spontaneous activity amplitude was larger than in the unimodal case.
Similarly, in a rabbit model of dilutional coagulopathy, PCC reduced blood loss and augmented peak thrombin generation after kidney trauma compared either with saline placebo or rFVIIa.
When these messages were poorly communicated or inconsistent or led parents to question clinical judgement or skill, their sense of loss was augmented.
The losses were augmented by players — including Henry — who could not keep from running into trouble with the coaches or the local authorities.
It is well known that stress-shielding can be manipulated by altering implant design, but less well appreciated that the development of bone anabolic agents may make it possible to reduce the severity of stress-shielding and the associated bone loss by augmenting the host skeleton through the use of locally or systemically delivered agents.
At the other end of the glucose tolerance continuum, we demonstrate potential for exercise- and diet-induced weight loss to augment insulin secretion in type 2 diabetic patients via improvements in β-cell function, in addition to elevated rates of insulin-stimulated glucose disposal and reduced fasting and postprandial hyperglycemia.
DL-TBOA co-treatment concentration-dependently augmented loss of cell viability induced by SN38, while strongly counteracting that induced by oxaliplatin, in both HCT116 and LoVo cells.
The Vietnamese government drafted 350,000 men into the military to replace earlier losses and augment its units along the border.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com