Using the criteria described in Materials and Methods, we identify 3584 homologs (out of 4425 Salmonella proteins in total) between these two highly related bacterial species, of which 3024 were found to be encoded by genes of conserved order (GCO) and 560 proteins encoded by genes that have lost their order (nGCO) (Additional file 1).
Furthermore, the lens fiber cells had lost their ordered lamination pattern, and swollen and liquefied fibers as well as vacuoles were seen throughout the lens (Fig. S4D).
Finally, we sub-sampled a set of sequences from the PDB set with the same size, amino acid and length distribution as that of the DisProt set to examine the ability of ordered proteins to retain or lose their ordered state.
After losing their top order cheaply, Sussex's hopes rested with Nash and Yardy but both were snared by left-arm spinner Keedy within three balls as Nash was stumped and Yardy was caught behind attempting a reverse sweep.
They are the women battling "fit-for-work tests", popping painkillers to get their bodies through a shift at work, or losing their careers in order to care for disabled children with minimal and shrinking support.
Mark Lewis, the solicitor for Milly Dowler's family, said: "People are losing their jobs in order to sacrifice themselves to save the real perpetrators … lots of good individuals have lost their jobs or will lose their jobs and the people who should have fallen on their swords are still there".
Pebble didn't have to run a separate campaign for the second-generation Steel, and those who had already committed to a Time could upgrade their order without losing their spot in line.
Under stressful conditions, such as extreme temperature, some proteins lose their higher order structures and related functions, and HSPs are synthesized to promote refolding of these denatured proteins.
Archive boxes store more, but its easier for papers to become loose and lose their filed order.
With the exception of the guinea pig (Cavia), rodents as an order appear to have lost or are losing their ENOSF1β homologues.
