Sentence examples for losing specificity from inspiring English sources
We observed a peptide-induced functional antibody response that, remarkably, exceeded the response induced by the native protein in outer membrane vesicles, without losing specificity for related strains.
In previous work [20], [21], [48], we presented implementations of multicompartment systems and resolved the problem of readjusting vesicle formation/composition as well as of losing specificity by using linkers consisting of biotinylated DNA single strands (biotin-ssDNA) that were anchored by long and flexible phospholipid-grafted biotinylated PEG tethers via streptavidin as a connector.
This enhances sensitivity without losing specificity.
CFFCP sensitivity in RA increased to 80.4% without losing specificity when positivity was considered as any positive anti-CFFCP status.
In principle, by simultaneously evoking perceptual surprise and utility surprise, our design gains sensitivity to either effect at the cost of losing specificity about which effect is responsible.
The most interesting result was that combining sEGFR and EGF, sensitivities of 88% in NSCLC and 100% in HNC were reached without losing specificity (97.8% in both cases).
The machine learning methods gained better sensitivities than human doctors at the cost of losing specificities.
Protein detection methods lose specificity when the protein target is immersed within a matrix of thousands of molecules having wide ranges of concentrations.
Regarding epitopes on one receptor, nanocarriers addressed with anti-TfR-R17 maintained brain and lung targeting in mice, compared with "free" antibody, while anti-TfR-8D3 nanocarriers lost specificity.
The anti-tumor activities and safety of TCR-transferred T cells can be improved by knocking out endogenous TCR, which avoids the use of affinity-enhanced TCRs that may lose specificity and cause severe adverse effects.
In a press release, Girirajan explained, "When individuals carrying classically-defined genetic syndromes were evaluated for features of autism, a high frequency of autism was observed, even among disorders not previously associated with autism, suggesting that the tools for diagnosing autism lose specificity when applied to individuals severely affected by other genetic syndromes".
