Sentence examples for losing interaction with from inspiring English sources

With followings in the tens of millions, many Youtubers see no value in surrendering control of their content and losing interaction with their audience in exchange for a salary.

The sulphonamide, however, sits lower in the active site losing interaction with Asn434, and the pyrazole group rotates slightly to accommodate the larger moiety at the 3- position.

Taken together these results indicate that the six broadly binding compounds along with earlier designs benefit from residing fully within the substrate envelope and thus decreasing the chance of losing interactions with a drug-resistant variant, rather than benefitting from an advantaged scaffold.

Instead, CUL3Δ403 459 auto-ubiquitylates and loses interaction with two important Cullin regulators: the COP9-signalosome and CAND1.

Moreover, RbLP-7A, in which all seven serine or threonine residues were substituted by alanine, completely lost interaction with Pin1.

Instead, CUL3Δ403 459 auto-ubiquitinates and loses interaction with two CUL3 regulators, namely the COP9-Signalosome and cullin-associated and neddylation-dissociated 1 (CAND1).

Several new NNRTIs incorporate flexibility in order to compensate for lost interactions with amino acid conferring mutations in RT.

Melanoma cells must lose interactions with keratinocytes in order to invade the dermis.

The Q155N mutant quickly lost interactions with Asn195 and Ala194 at the helix 2 region, as indicated by the continuous increase in pairwise residue distances; however, the interactions between Asn155 and Glu159 were well conserved.

However, a small portion of the isolated RNPs was also in a loose helical filament form, suggesting that the RNPs become unstable upon losing the interaction with the transmembrane M protein and the envelope (Risco et al., 1998; Barcena et al., 2009).

As a result, the E-loop in A461T moves away from the active site, losing its interaction with the D′E-loop in the N-SH2 domain.