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The curse is that I will pass through the stages of losing function in slow motion.
It is one of the last painted works she was able to complete before losing function on the right side of her body.
Disorder, which is encoded by a much wider portion of sequence space as compared to order, can indeed represent a strategy by which genes encoding overlapping reading frames can lessen evolutionary constraints imposed on their sequence by the overlap, allowing the encoded overlapping protein products to sample a wider sequence space without losing function.
Few studies have reported on the association between alcohol phenotypes and ADH1A polymorphisms, perhaps reflecting the current belief that ADH1A enzymes are most active in ethanol metabolism during fetal and early life, gradually losing function in adulthood (63).
The shift from 37°C to 27°C was to allow adequate rescue of CFTR-ΔF protein so that we could see the detrimental impact of losing function of a presumed pro-biogenesis factor.
Of course, the effect of losing function at a given gene may also depend on the genomic background, i.e. other variants present in the same genome, and therefore dispensability may be a complex phenomenon.
Similar(51)
temperature-sensitive protein A protein that is functional at one temperature but loses function at another (usually higher) temperature.
Moreover, neurons that are still present may be impaired and functionally unable to compensate for lost function.
Transdifferentiation of an individual's own cells into functional differentiated cells to replace an organ's lost function would be a personalized approach to therapeutics.
Others take longer, get damage and lose function.
The tissue was clearly attempting to recover lost function.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com