Sentence examples for loose function from inspiring English sources

This was an important feature since several mammalian cells transfected with other natural or recombinant photoproteins, tended to loose function over time in the absence of selective pressure (unpublished).

Usually the fibrosis driving process occurs silently and is not perceived until the allograft starts to loose function or a surveillance renal biopsy is performed.

Other proteins, for example actins, show little amino acid variation (~5-7% across metazoans, [ 4]), and tend to loose function entirely rather than provide altered function in response to change in their amino acid sequence [ 5].

We now know that among type 1 diabetic patients enrolled in clinical trials to preserve β-cell function, it is unusual for control or placebo-treated subjects starting with a reasonable amount of C-peptide at diagnosis to completely loose function in the first 2 years (3– 13).

Previous studies have shown that younger duplicated genes tend to loose functions more often than older duplicated genes that often gained new functions (e.g., stress responsiveness in Zou et al. 2009).

Early studies [e.g. [ 51]] have contrasted the alternative models of neofunctionalization (i.e. one gene copy stays conserved, the other evolves a novel function) and subfunctionalization (i.e. both gene copies loose part of their functions and have to complement each other).

It is still necessary for the mass estimation of loose parts, one function of a loose part monitoring system, to develop a new method due to the high estimation error of conventional methods such as Hertz's impact theory and the frequency ratio method.

In this animal model as well as in inherited retinal degeneration, the "final common pathway" of photoreceptor cell death is considered to be apoptosis [35], [36] although cones in retinal degeneration (RD), even if they loose their function, can survive for very long time, i.e. cone apoptosis does not occur necessarily in some RD patients [37].

In the following 2 3 weeks, CD8 T cells contract in number and, while maintaining responsiveness to antigen-specific stimulation, loose cytotoxic function.

Virus-specific T cells are usually able to kill virus-infected cells, but during chronic infections cluster of differentiation (CD 8+ T cells loose their function.

Strikingly, similarity between repeat 1,7 and 11 and those within the duplicated triplet block in human KNL1 correlates with their capacity to recruit BUB proteins, suggesting that diverged repeats loose their function (Vleugel et al. 2013, 2015 ).