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Open image in new window Fig. 4 Half-quadrupled configuration: quadrupled loop on one side and doubled loop on the other, obtaining a "4 + 2" preparation.
Two sutures with N.02 Fiberwire were then passed on each side and secured with a buried-knot technique [13], obtaining a quadrupled loop on one side and a doubled loop on the other one ("4 + 2" configuration) (Fig. 4).
The pre-miRNA terminal loop on one end induces hDicer's N-terminal domain structural change, on the other end, helps pre-miRNA's stem region align against hDicer's RNase domain.
Yesterday we closed the loop on one rumour — that maps and navigation app maker Skobbler had been approached by several "major tech companies" interested in making an acquisition — confirming that Telenav has acquired the Berlin-based startup for just shy of $24 million.
(L[X]) — the free product of (L) with the free loop on one generator (X); (L_a) and (R_a) — the operators of left and right multiplication, respectively, by (ain L) in (L[X]); (mathrm {U}(L)) — the group of self-maps of (L[X]) generated by the (L_a) and (R_a) for all (ain L); (mathrm {U}(L _e) — the stabilizer of the identity in (L[X]).
Introduce the following notation: (L[X]) — the free product of (L) with the free loop on one generator (X); (L_a) and (R_a) — the operators of left and right multiplication, respectively, by (ain L) in (L[X]); (mathrm {U}(L)) — the group of self-maps of (L[X]) generated by the (L_a) and (R_a) for all (ain L); (mathrm {U}(L _e) — the stabilizer of the identity in (L[X]).
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Three of the flexible loops on one side of the protein are surface-exposed and have proved to be a convenient interface for binding ligands of interest (Fig. 1A).
As is written in Exodus 26:5 "You shall make 50 loops on one curtain, and you shall make 50 loops on the second that is to join with it.
In accordance to the secondary structures found with other LncRNAs [ 9, 27, 28] all the stable structures have long stems and big loops on one side (Fig. 5).
The molecular mechanism of the biological clock is conserved across different groups of organisms [ 125], exemplified by positive and negative transcriptional feedback loops on one hand, and the redox state of peroxiredoxin on the other hand [ 126].
At one point the production editor, Bob Poulton, patted me on the shoulder and said: 'We kept you out of the loop on that one' as I started arguing about another headline.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com