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(a) The structure of uncleaved GP (PDB 5JQ3) showing the position of the β17-β18 β17-β18und to the 310 pocket.
A related issue is nested loop structures with loop bound interdependencies, which are difficult to precisely incorporate in the timing model.
Symbolic execution unrolls loops, hence, for most cases, neither loop bound annotations nor complementary loop bound analyses are necessary (see Section 5 for examples) except when the bound is dependent on, for example, I/O or the unrolling exceeds the specified analysis depth.
Note that we did not need to provide loop bound annotations in any of the examples nor did we reach the default search depth (corresponding to 100 branches) during analysis.
In cases where annotations are necessary, SYMRT offers (simple) comment-based loop bound annotations on the form //@loopbound = bound; SYMRT will unroll the loop up to the specified bound and explicitly break it.
In the loop bound by helix III there are twelve nucleotides, and the purine at position 37 is a G in metazoans.
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The catalytically active A-site with a conserved GGD /E EF loop binds one monomer of GTP, which is the substrate.
Calder rarely used solder; when he needed to join strips of metal, he linked them with loops, bound them with snippets of wire or fashioned rivets.
Of AG loops bound by GU or UG pairs, only 5′U AGG/3′G GAU adopts wobble UG closing pairs and apparently weak imino AG pairs in the loop.
The RRMs of U1-A and U1-70k haveryery similar structures (the β-strands and α-helices of the two RRMs superimpose with an rmsd of 0.70 Å) whereas the RNA loops bound to these RRMs have strikingly different structures.
Such sequences can be due to imperfect antibody specificity or to indirect DNA-binding by the antibody via a protein complex or via chromatin loops bound jointly by the antibody and another DNA-binding protein [ 19].
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com