Sentence examples for loop blocking from inspiring English sources

Into the early morning hours of Wednesday, protesters led clusters of police officers on a march through the streets of Chicago's Loop, blocking intersections, chanting outside a police station and, along a major road to the city's largest highways, unfurling a banner that cited deaths at the hands of the police.

Selective inhibition of the BRAF oncoprotein reduced a negative feedback loop blocking EGFR.

Hypotheses for this central/peripheral discrepancy include recruitment of NO from the brain towards the burn site, and/or a negative feedback loop blocking central NO because of its oxidative and free-radical deleterious effects [ 55].

The skyscrapers in the Loop blocked microwave links.

Although we have many reforms already under our belt, and many more on our plate, our appetite for reform remains hearty.MASAMICHI KONODirectorInternational Affairs DivisionFSATokyoIn the loopSIR You misrepresent OFTEL's achievements in extending competition through unbundling the local loop ("Blocked", September 30th).

Like imatinib, AMN107 binds to the inactive conformation of the Abl tyrosine kinase, with P-loop folding over the ATP-binding site, and the activation-loop blocking the substrate binding site, to disrupt the ATP-phosphate-binding site and inhibit the catalytic activity of the enzyme (Manley et al, 2005).

This suggests that acetylation of the flexible loop acts as a regulatory mechanism: the loop blocks active site of the HAT domain in p300, is autoacetylated and released so that the active site is not blocked anymore, and p300 is activated to acetylate other substrates.

Additional Live and Loop blocks will be available as well for $79, snapping onto the base Lightpad to create a full system.

We have previously shown in vitro that the GLUT2 loop blocks glucose stimulation of sensitive gene transcription.

Previous studies suggest the following model for Trk activation: in the ligand-unbound state, the activation loop blocks access of substrates to the active site of the kinase domain.

The loop caps prevented direct interactions between G-tetrads and K+ ions from environment, suggesting that the loop bases blocking the pathways should realign to permit an access of cations to the central channel.