loop accumulation

USAGE SUMMARY

"loop accumulation" is correct and usable in written English. You can use it in contexts related to programming, data processing, or any situation involving iterative processes. For example: "The algorithm demonstrated significant loop accumulation, leading to performance issues." Alternative expressions include "iteration buildup," "repetition accumulation," and "cycle accumulation."

✓ Grammatically correct

Science

Academia

Human-verified examples from authoritative sources

Exact Expressions

3 human-written examples

Additionally, a simple recursive incremental relation is set to count the loop accumulation on the precipitates.

Materials Science and Engineering: A

Recent work has revealed a role of H3S10 phosphorylation in transcription-associated genomic instability as a result of R loop accumulation [106].

Biochimica et Biophysica Acta - General Subjects

This would imply that the mechanism of suppression would be influenced by RNase H overexpression, as in the case of R loop accumulation and transcriptional and recombination abnormalities in THO mutants (Huertas and Aguilera, 2003).

Cell

Human-verified similar examples from authoritative sources

Similar Expressions

57 human-written examples

Bhatia, V. et al. BRCA2 prevents R-loop accumulation and associates with TREX-2 mRNA export factor PCID2. Nature 511, 362 365 (2014).

Nature

Together, our findings support a model in which R-loop accumulation and subsequent DNA damage sequesters HR factors, thereby compromising HR repair at endogenously or exogenously induced DNA damage sites, leading to genome instability.

Stanford University

TOP1 is required for plant development, but little is known about its function in preventing co-transcriptional R-loop accumulation in various biological processes in plants.

Molecular Plant

DNA topoisomerase 1 (TOP1), an essential manipulator of DNA topology during RNA transcription and DNA replication processes, can prevent R-loop accumulation by removing the positive and negative DNA supercoiling that is made by RNA polymerases during transcription.

Molecular Plant

In addition, the increased demand for rRNA in RP-deficient cells might hyper-activate rDNA units, increasing the probability of topological stress occurring that would result in fork reversal and R-loop accumulation (Bermejo et al., 2012).

DMM Disease Models and Mechanisms

Topoisomerase I (Drolet, 2006; Tuduri et al., 2009), RNase H Wahbaa et al., 2011), and Senataxin (Sen1 in budding yeast) (Mischo et al., 2011; Skourti-Stathaki et al., 2011; Stirling et al., 2012) have been involved in suppressing R-loop accumulation.

Cell

R-loop accumulation is enhanced in the absence of mRNA biogenesis factors (Paulsen et al., 2009; Stirling et al., 2012), including the THO/TREX-2 complexes (Domínguez-Sánchez et al., 2011; Huertas and Aguilera, 2003) and the SR protein SRSF1 (Li and Manley, 2005).

Cell

The enhancement of loop mRNA accumulation by P38 was so great that loop mRNA in wild type plants was barely detectable at the exposure appropriate for the samples from P38-expressing plants (Figure 4B, lanes 7 9), although it was clearly visible at a 3-fold longer exposure (Figure 4B, image of lanes 7 9 labeled "loop 3x exp").

Plosone

Expert writing Tips

Best practice

Use "loop accumulation" when referring to the state of having many loops, while using "accumulation of loops" when you want to emphasize the ongoing process.

Common error

Do not use "looping accumulation" when you mean the buildup of physical loops. "Looping accumulation" suggests that the act of accumulating itself is repeating in a cycle, whereas "loop accumulation" correctly identifies that the objects being accumulated are loops.

Linguistic Context

The phrase "loop accumulation" functions as a compound noun. In this structure, "loop" acts as a noun adjunct modifying the head noun "accumulation". According to Ludwig, it is commonly used as a subject or a direct object in technical sentences to quantify a specific structural state.

Expression frequency: Rare

Frequent in

Science

85%

Academia

10%

Formal & Business

5%

Less common in

News & Media

3%

Wiki

1%

Social Media

1%

Ludwig's WRAP-UP

In conclusion, "loop accumulation" is a highly specialized and grammatically correct term primarily found in scientific and academic contexts. Analysis from Ludwig AI confirms that while it is a rare phrase in general English, it is indispensable in fields like molecular biology and materials science. It typically describes the buildup of structures like R-loops or dislocation loops, often implying a change in state or potential instability. Writers should ensure the specific type of loop is identified to maintain the high level of precision expected in the professional registers where this phrase typically resides. Alternatives like "buildup of loops" may be used for slightly better flow in general descriptions.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

accumulation of loops

Uses a prepositional structure to emphasize the process of gathering.

loop buildup

More informal but direct, often used in physical or mechanical contexts.

buildup of loops

A prepositional variation of the buildup synonym.

loop density increase

Focuses on the spatial concentration rather than just the quantity.

loop formation

Describes the creation process rather than the resultant collection.

R-loop accumulation

A highly specific biological term referring to RNA-DNA hybrids.

cycle accumulation

Swaps the physical shape for a temporal or logical term often used in computing.

iterative buildup

Focuses on the repetitive nature of the accumulation process.

repetition accumulation

Uses a more abstract term for the recurring elements.

loop clustering

Implies that the loops are gathering in a specific location or group.

FAQs

How do I use "loop accumulation" in a sentence?

You can use it as a noun phrase to describe a result, for example: "The researchers observed significant "loop accumulation" in the mutant cells."

What can I say instead of "loop accumulation"?

Depending on your context, you can use alternatives like "loop buildup", "accumulation of loops" or "increased loop density".

Is "loop accumulation" common in biology?

Yes, it is very common in genomics, specifically referring to "R-loop accumulation", which can lead to DNA damage and genome instability.

What is the difference between "loop accumulation" and "accumulated loops"?

"loop accumulation" refers to the phenomenon or process of the buildup, while "accumulated loops" refers directly to the loops that have already been gathered.