The other is to look for sequences similar to those found in known genes.
The researchers compared the dogs' DNA, looking for sequences that differed by a single base, known as single-nucleotide polymorphisms.
We are looking for sequences that generate the space of sequences of duration T = 1, with more than 90% of their energy inside bandwidth [-F, F], with F = 2. Signals are sampled with 500 time samples over [0, 1].
They found 164 such sequences and matched them against data showing what genes are active in embryos, looking for sequences that seemed to be active in early male embryos.
As a first approach to characterize grapevine class II "copy-and-paste" transposons we used a homology-based strategy to look for sequences with similarities with known transposases.
Therefore, DLX genes can be easily identified in non-annotated genomes by looking for sequences showing homology with the canonical DLX homeodomain sequence, and then by filtering for those showing these motifs.
In the third approach, we looked for sequences that were conserved across ten primate genomes.
When looking for sequences with common features across individuals (or time points), it is important to consider statistical power.
Where such discrimination between partial sequences, splice variants, predicted proteins or allelic forms is made by subsequent experiments, it will first be required to compare all of the protein sequences together in the same database to look for sequences unique to specific proteins.
We then tested whether N. vespilloides has DNA methylation by looking for sequences coding for the enzymes responsible, DNA methyltransferases, and by using whole-genome bisulfite sequencing with the hypothesis that like T. castaneum (Zemach et al. 2010), N. vespilloides would lack DNA methylation.
