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Most recently they have been investigating circuitry rather than specific locations, looking at pathways and connections that are central in creating social emotions, a moral sense, even the feeling of free will.
He hopes the model will be useful for future predictions along these lines, such as looking at pathways of disease progression.
This article contributes to the existing literature on participatory EWS by looking at pathways for relevant community engagement and moves beyond existing approaches by questioning the current conception of EWS as tools for risk detection and warning issuance.
We could assemble all of these mutations we found in a way that would enable us to start looking at pathways underlying the formation and function of tissues.
But, by looking at pathways also clustered with Nucleotide Excision Repair in the Consolidation Results grid, one might find connections between enriched and non-enriched pathways.
Looking at pathways, we found a IPA-inferred pathway that is related to [Ca2+]i homeostasis (Fig. 4A).
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This, for example, pointed us to the apoptosis pathways in the comparison between the two diet groups at t = 0, which would not have been found by looking at pathway enrichment alone.
You look at pathways to achieve that goal.
The analysis of isolated cultures may therefore provide an incomplete picture of lin pathway evolution and need to be interpreted in light of other approaches, such as metagenome sequencing, that look at pathway organization in soil populations.
Finally, we looked at pathway enrichment through p-values (see Additional file 4) and performed a qualitative evaluation aimed to characterize each module according to inherently cohesive (i.e. intra-modular, self-contained) versus cross-talk (i.e. inter-modular, communicative) dynamics.
The lab has lots of data on how individual pathways work, but no one was looking at the pathways as an interacting system.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com