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To investigate regional patterns of brain change associated with longitudinal change in cognition, an additional analysis was done using cognitive test scores as dependent variables.
In this analysis, we explored the relation between longitudinal change and selected biomarkers.
Her research interests include applying the methods of behavioral genetics to investigations of cognitive aging and biological markers of the aging process and the methods of longitudinal analysis to twin data to investigate genetic and environmental influences on longitudinal change.
Temporal patterns of longitudinal change in aging brain function.
Longitudinal change in TSQM scores approximated a normal distribution, thus parametric testing for differences among Patient Impression of Change categories was performed using analysis of variance (ANOVA).
Deformable image registration allows volume of interest (VOI)- and voxel-based analysis of longitudinal changes in fluorodeoxyglucose (FDG) tumor uptake in patients with non-small cell lung cancer (NSCLC).
141 (76%) specimens were available for analysis of longitudinal changes in MMP/TIMP concentrations: 66/94 (70%) were from placebo and 75/91 (82%) from dexamethasone group patients (a mean of 3.8 (+/−1.2) samples per patient).
Analysis of longitudinal changes in AGD showed that no further rise in AGD after 18 months of age (Table 3).
Analysis of longitudinal changes indicated the role limitations due to physical and emotional problems of the SF-36 exhibited the highest improvement rate.
Because a previous study demonstrated that blood contamination influences levels of total α-syn [ 28], 25 subjects with at least 1 sample containing >200 ng/ml hemoglobin, the level at which blood α-syn confounds CSF α-syn levels, were excluded from analysis comparing longitudinal changes in pS129, α-syn or pS129/α-syn ratio.
We analysed longitudinal changes in physiological outcomes using repeated measures analysis of variance (corrected for site).
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