Exact(11)
In longevity experiments Amberlyst 15 was reused once with no loss in catalytic activity, while successive experiments demonstrated decreases in catalytic activity.
"One of the nasty secrets of the field is that most mouse longevity experiments are done only once in one lab on one genetic background," said Steven Austad, an expert on aging at the University of Texas Health Science Center, who was not involved in the research.
Thus, these types of longevity experiments have precedence.
Longevity experiments revealed that the tmem135 (ok1646) mutants lived for a significantly shorter time than wild-type worms, both at 20°C (normal growth conditions) and 15°C (low temperature), while TMEM135::GFP-overexpressing worms lived for a significantly longer time than wild-type worms at 15°C (Fig. 6C and 6D).
Log-rank test was used for analysis of longevity experiments.
Survival records of longevity experiments are a key component in research on aging.
Similar(49)
As in the longevity experiment, each MNIL was represented with 14 16 individuals of each sex (approximately 2100 individuals in total).
The design of the longevity experiment allowed us to measure and compare selected males influence on females' mortality.
Since the results of the longevity experiment did not reveal any effects by melatonin, we further tested for putative short-time effects of melatonin under acute stress conditions.
31 Bmal1−/− mice (both genders) were treated with rapatar and 73 Bmal1−/− mice (both genders) treated with control solution were used for the longevity experiment.
Perhaps, the only exception to this could be rapamycin, which led to modest but consistent 4 14% increases in maximum longevity (90th percentile survival age) after parallel replication of the longevity experiment at three institutions (Harrison et al., 2009).
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