Sentence examples for longevity effects from inspiring English sources

Furthermore, the mitochondrial changes and longevity effects induced by CA are conserved across different species.

SIRT1 plays a key role in the longevity effects elicited by calorie restriction.

They suppress genome-wide transcription, yet upregulate a select set of proteins related to energy metabolism and pro-survival mechanisms, and therefore play a key role in the longevity effects elicited by calorie restriction.

To investigate whether metformin extends median lifespan by acting through the insulin signaling pathway, we tested a daf-16 null mutant strain that lacks the FOXO transcription factor needed for the longevity effects of the insulin signaling pathway (Fig. 1C).

Of course, hydrogen peroxide and superoxide are also likely to affect signaling, including through the insulin-like growth factor pathway, and changing their relative abundance might have signaling effects that contribute to the observed fitness effects as well as explaining some of the longevity effects [29].

Another fundamental question involves the downstream pathways of mTORC1 that mediate the longevity effects.

A gene called sir-2, for silent information regulator-2, turned out to be responsible for this longevity effect.

For now, gerontologist Richard Weindruch, who heads the Wisconsin monkey project, isn't ready to give up on a longevity effect.

Therefore, the use of PEGylated liposomes could prolong the circulation time in blood and longevity effect of liposomes on Sal B was increased by PEG.

Here, we assayed the longevity effect of compound Otophylloside B (Ot B), a C-21 steroidal glycoside isolated from Qingyangshen, in Caenorhabditis elegans, which is a popular model for aging research.

The hypothesis is that 5178A (ND2: Leu237Met) is associated with an overall protective effect for both groups, but the additional mutation at 14979C in D4a is correlated with a significant additional longevity effect in D4a.