Sentence examples for longevity effect from inspiring English sources

A gene called sir-2, for silent information regulator-2, turned out to be responsible for this longevity effect.

For now, gerontologist Richard Weindruch, who heads the Wisconsin monkey project, isn't ready to give up on a longevity effect.

Therefore, the use of PEGylated liposomes could prolong the circulation time in blood and longevity effect of liposomes on Sal B was increased by PEG.

Here, we assayed the longevity effect of compound Otophylloside B (Ot B), a C-21 steroidal glycoside isolated from Qingyangshen, in Caenorhabditis elegans, which is a popular model for aging research.

Increased Sir2 levels have been associated with increased lifespan in yeast, flies, and worms [3], 4, 50 and Sirt1is a leading contender for proteins responsible for the longevity effect of CR in rodents [26], [51].

We then asked whether the longevity effect of increased HIF-1 protein was independent of the DAF-2 insulin-like signaling pathway by crossing the hif-1(P621G) transgene to a long-lived daf-2 loss-of-function mutant.

Furthermore, the mitochondrial changes and longevity effects induced by CA are conserved across different species.

SIRT1 plays a key role in the longevity effects elicited by calorie restriction.

To investigate whether metformin extends median lifespan by acting through the insulin signaling pathway, we tested a daf-16 null mutant strain that lacks the FOXO transcription factor needed for the longevity effects of the insulin signaling pathway (Fig. 1C).

Another fundamental question involves the downstream pathways of mTORC1 that mediate the longevity effects.

PHA-4 is not required for IIS pathway-mediated longevity effects.