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When a nucleotide is incorporated by the DNA polymerase, the fluorescent tag is cleaved off, which diffuses out of the observation area of the ZMW where its fluorescence is no longer observable.
Secondly, these NWs are no longer observable.
For longer trenches this effect is weaker or no longer observable.
After anion exchange, the vibration of nitrate is no longer observable.
As the cure intensity increases, the rate of phase separation increases such that the early stages of spinodal decomposition are no longer observable.
It is not known if mechanical wear affected other cited studies or if mechanical damage is no longer observable at longer time points.
Similar(42)
In our experiment, with the longer observation time of several minutes, the electron dose may accumulate to beyond a limit that affects the observable gold crystal morphology.
Finally, the marketed test cases selected in this study have observable clinical response after a single dose, but this may not be true for many other therapeutic areas that may require multiple doses and longer observation periods.
For a hidden Markov model (HMM), we generalize to where the states are no longer directly observable (but still 1st-order Markov), and for each state, say, we have a statistical linkage to a random variable,, that has an observable base emission, with the standard (0th-order) Markov assumption on prior emissions (see [27] for clique-HMM generalizations).
If data from their hybrid half-siblings were added to the analysis (same hatchery mothers, wild fathers; total n = 27, 21, 24, 9, 15, 24), there was no longer an observable difference in mass (P = 0.2, Mann-Whitney U test).
Pulsar phenomena apparently last much longer than the observable supernova remnants in which they were born, since well more than 1,500 pulsars have been cataloged and only a few are associated with well-known remnants.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com