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The inability of long-term poisoning of TOP2A by bDMC could be due to the rapid metabolism of the molecule inside the cell.
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The study flatly states, for example, that PCB's are a dangerous and potent long-term poison in the environment.
From the long term poisons in Ron Angel's Chemical Workers' Song and WDE's Asbestos Lead Asbestos, to the short-term irritant of squid ink in the eye (as relayed here by Hank Snow), danger can be found in all kinds of working environments.
However, two ground-nesting species, white-rumped and rufous-necked snowfinches, showed positive associations with the density of pika burrows, indicating that long-term pika poisoning could reduce the density of these species by reducing the density of pika burrows.
Moreover, the presence of Au can significantly enhance the long-term stability and poisoning tolerance during the electro-oxidation of glucose.
Long-term, they are poison".
Following acute poisoning, long-term sequelae often occur.
Timely diagnosis and identification of the source of exposure are critical in preventing the long-term consequences of lead poisoning.
Studies of pesticide neurotoxicity have typically evaluated either the long-term sequelae of pesticide poisoning or the effects of occupational exposure (Table 1).
In the overall long-term management of lead poisoning, chelation therapy can have short-term benefits; however, these benefits must be accompanied by drastic reduction in environmental exposure to lead if therapy is to have any long-term benefit.
Chelation therapy for hundreds of children, soil replacement, and an education campaign to discourage processing ore inside homes may now have radically reduced child mortality in the hardest-hit villages, but the long-term effect of lead poisoning on the surviving children remains to be seen.
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