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Intriguingly, he found that these mutant mice were deficient in long-term memory storage.
This is not exactly practical in the real world, nor will it likely lead to long-term memory storage.
Bontempi, B., Laurent-Demir, C., Destrade, C. & Jaffard, R. Time-dependent reorganization of brain circuitry underlying long-term memory storage.
Role of norepinephrine in mediating stress hormone regulation of long-term memory storage: a critical involvement of the amygdala.
This mechanism explains how signals between neurons stimulate production of the protein building blocks needed for long-term memory storage.
The new test, developed by Daniel Alkon, scientific director of BRNI, targets a group of enzymes called PKCs, which are involved in long-term memory storage.
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This technique helps information to be moved from short term memory into long term memory storage.
"There was all this evidence coming out that changes in gene expression were important for things like long-term-memory storage," Rob Malenka says.
One idea is that sleep is critical for the maintenance and storage of long-term memories.
In a study to appear in the June 10 issue of Neuron, neuroscientists at the Picower Center for Learning and Memory at MIT show for the first time that storage of long-term memories depends on the size and shape of synapses among neurons in the outer part of the brain, the cerebral cortex.
During sleep, newly acquired memory traces are not only strengthened in distinct neural circuits, but additional new memory traces are also established for long-term storage and integrated within pre-existing long-term memories ("consolidation", see [ 65, 69]).
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