But there are also virtues to the legacy process, primarily because close association with long-standing institutional practices lends long-term stability to identifier schemes.
The findings that 50% of patients randomized to EX/RP had minimal symptoms at 6-month maintenance, a rate double that of prior studies, suggests that EX/RP maintenance helps maximize long-term outcome.ClinicalTrials.gov identifier: NCT00389493.
Further follow-up is needed to assess long-term effects on health outcomes.clinicaltrials.gov Identifier: NCT01608490.
Further studies are needed to assess long-term efficacy and safety.clinicaltrials.gov Identifier: NCT01984424.
With the aim of clarifying this controversy, we analyzed the clinical and genetic data generated in the PREDICT and the PREDICT long-term follow-up studies (ClinicalTrials.gov Identifiers: NCT00256126 and NCT00699855) (16).
In the pivotal TEMPO 3 4 (Tolvaptan Efficacy and Safety in Management of Autosomal Dominant Polycystic Kidney Disease and its Outcomes) trial (ClinicalTrials.gov identifier: NCT00428948 [ 24]), long-term treatment with tolvaptan was associated with favorable outcomes in subjects with early ADPKD.
ITF2357 has been tested in Phase II clinical trial for Hodgkin's lymphoma, chronic myeloproliferative diseases and juvenile idiopathic arthritis, and is currently undergoing evaluation for long-term study on chronic myeloproliferative neoplasm (ClinicalTrials.gov Identifier: NCT01761968).
PuLsE was an international, multicenter, prospective, randomized, parallel-group, open-label, and long-term (2 years) effectiveness study (Fig. 1; ClinicalTrials.gov identifier: NCT00522418).
Identifier NCT00533897 Patients with rheumatoid arthritis (RA) receive long-term treatment and sometimes require interruption of therapy for example, in the event of surgery or side effects.
Over 90percentt of these cases involve apps transmitting identifiers that cannot be changed or deleted, like hardware serial numbers thereby enabling long-term tracking.
A Long-term, Phase 2, Multicenter, Randomized, Open-label, Comparative Safety Study of LY2140023 Versus Atypical Antipsychotic Standard of Care in Patients with DSM-IV-TR Schizophrenia ClinicalTrials.gov identifier: NCT00845026.
