Sentence examples for long-term differentiation from inspiring English sources

Biologic characterization has been performed with MC3T3-E1 pre-osteoblastic cells in terms of cell adhesion and long-term differentiation.

While the mechanism remains unclear, laminin-related cellular pathways were found to be significantly enhanced and the graphene substrates were observed to act as an excellent cell-adhesion layer especially for the long-term differentiation process.

These data support the idea that acute exposure to a high dose of TGF will induce functional and long-term differentiation of stem cell populations, and further our efforts to improve cartilage repair in vivo.

Finally, optimized conditions of the cell-laden collagen-Ph hydrogel resulted in not only improving the long-term differentiation of transplanted MSCs into mineralized osteoblasts, but the collagen-Ph hydrogel also improved an increased of adipocytes within the vascularized bioengineered tissue in a mouse after 1 month of implantation.

To conclude, a chip-based platform for long-term differentiation studies on mouse and human ES cells and adult neural stem cells was demonstrated.

Implications of this, with respect to the stability of the undifferentiated state and long-term differentiation potential of iPSCs, warrant further studies.

These results indicated that the cells in the aggregates change their morphology and the fibrils were replaced with cartilaginous ECM during long term differentiation.

However, the large dilution effects of the culture are likely to prevent significant long term differentiation of PS derivatives in these conditions and long term culture in N2B27 selects against PS cells.

Using conditional ablation, Challen et al have demonstrated that Dnmt3a loss in mice impairs long-term HSC differentiation, upregulates multipotency genes and downregulates differentiation factors in HSC [ 57].

These results highlight the importance of initial biomaterial surface chemistry on long-term functional differentiation of adult stem cells, and suggest that surface properties are a critical parameter that must be considered in the design of biomaterials for stem cell-based regenerative medicine strategies.

It won't create long-term competitive differentiation, and it won't rally your employees to deliver better service.