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The phrase 'long-term changes' is correct and usable in written English.
You can use it to indicate changes that have a lasting effect, such as adjustments to processes, policies, regulations, or behavior. For example: “We need to make long-term changes to increase safety in our workplace.”.
Exact(60)
What about long-term changes?
CO2 changes, however, do cause long-term changes in CO2.
Understands long-term changes and recurring patterns in world history.
Long-term changes were statistically, but not clinically, significant.
By the end of 2006, it will propose long-term changes in the program.
Any long-term changes must involve major cities from both hemispheres.
This is good news, because with climate change, it's these long-term changes we're worried about:.
The panel said it would recommend long-term changes in another report next spring.
With practice and repetition, he said, this could lead to "long-term changes in the brain".
Ongoing turbulence will make it harder to focus on long-term changes.
Pollution of air and water is contributing to long-term changes in weather.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com