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Leanness is probably an indicator of the severity of diabetes and long standing exposure to hyperglycemia.
In a population, subgroup dioxin levels may also reflect long-standing historical exposure, rather than simply recent or contemporary exposure.
It appears possible that both IgG2 and IgG4 subtypes are induced in IAC upon long-standing antigen exposure.
Emmett et al. (2006) studied 371 residents of a community with long-standing environmental exposure to PFOA and found a median serum PFOA concentration of 181 571 ng/mL but no association between serum PFOA and a history of thyroid disease.
This pattern's similarity in men and women and its maintenance over time suggest that distribution of stomach cancer here in Spain could be related to long-standing environmental exposures shared by both sexes, as gastric cancer is known to be the result of decades of interaction between chronic inflammation and exposure to carcinogens.
This implies that PCAINs are "de-noised filtrates" of PCMs - a result that corroborates the long-standing notion that exposure to solvent correlates with evolution-driven amino acid substitution [23].
Thus, these results challenge the long-standing assumption that effects of exposure to endocrine disruptors during adulthood are reversible after exposure ceases.
In this respect, two long-standing hypotheses stand out.
And the purpose of those efforts -- the problem they set out to solve -- is to ease the public relations crisis caused by the exposure of long-standing human rights violations.
Moreover, a long-standing hypothesis links chronic GC exposure to unhealthy hippocampal aging/Alzheimer disease (AD) (16– 20).
Moreover, evidence is inconsistent regarding the long-standing hypothesis that chronic GC exposure promotes brain aging/Alzheimer disease.
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Justyna Jupowicz-Kozak
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