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Recent efforts to improve on the methodology target its main weaknesses: low sensitivity and long time requirements.
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It also repeals a long-time requirement that EPA select the "least burdensome" method of regulating a toxic substance.
It aims to make chemical safety reviews purely science-based, by eliminating a long-time requirement that EPA weigh regulatory costs in the safety review process.
Despite its long-time requirement, bioremediation is an alternative low-cost technology, whose efficacy is often enhanced with preliminary mild physical chemical remediation methods [4, 5].
Furthermore, long simulation time requirements for daylighting significantly hinder the realization of many benefits from MDO.
The design of heat exchangers is important as they need be designed in a proper way to achieve efficient cleaning for both short and long running time requirements.
Current systems for determining the symmetry of the void distribution in distributed flows either suffer from very long measurement time requirements or cause significant disturbances to the flow.
Assessment of the fatigue behavior of composite materials is a complex and tedious task due to its heterogeneous nature as well as the long testing time requirement.
The general deficit in terms of research on social competences has been known about for a long time while the requirements for these competences as a basis for vocational and specialist professionalism are growing.
However, for many bioinformatics applications where the number of states in the model M is large, the connectivity T max of the model high or the training sequences are long, these memory and time requirements are too large to allow automatic parameter training using this algorithm.
Yet another interpretation – turning the tree on its head – is that the M3 molecules may not only go back a long time, but the structural requirements imposed by their function may be sufficiently tight that their evolution could have been much slower than that of the other molecules on the tree.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com