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The second is long time necessary to synchronize numerous modifications of the pheromone matrix.
A slow rate of curing and the long time necessary to achieve full strength has led cold asphalt mixes (CAM) to be considered poorer in comparison to hot mix asphalt over the last decades.
Efficient viral vectors allow to bypass the limitations of other expression methods, such as the low yield obtained with stable transgenic plants or standard transient expression methods, and the long time necessary for development of stable transgenic lines.
Despite the advantages of enzymatic catalysis, there are obstacles that prevent enzymatic process to be used commercially for biodiesel production: the high lipase price, the long time necessary for the synthesis reaction of biodiesel, and possible inhibition and/or denaturation of the enzyme by the alcohol [37],[37].
A disadvantage of the method is the long time necessary for sorting and the need for placing the whole procedure in a cleanroom environment, including additional requirements for the design of the sorters.
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The treatment at Johns Hopkins involves laxatives — for a long time, when necessary — combined with analyzing the diet and increasing fiber, as well as drinking water, if the child's intake is inadequate.
The low-permeability characteristics make the conventional steady-state way impractical, because a very long time is necessary for building each steady-state saturation profile.
But, when this method was applied to small curved holes less than 6 mm in diameter, it became clear that long time was necessary.
In order to obtain highly crystalline TiO2 at low temperature, a long time is necessary to get pure anatase or anatase rutile phase mixture, and days or even longer time for the formation of rutile phase in traditional sol gel process [10 12].
In a direct tube-bond formation mechanism, the interaction between the loosely formed contact pairs may be too weak to hold the newly added tubulin dimer for sufficiently long time before necessary conformational reorganization takes place to form the stable tube bond, which would result in very low lateral association rate.
In addition, the long time interval necessary for the grape to complete one generation, together with its vegetative propagation, makes it difficult to match the evolutionary rates of microbial or insect pests, which in vineyards are boosted by massive use of chemicals [35].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com