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Due to the expense and the long time frame of much astronomical research, astronomers face a great deal of professional risk, in both research and career terms.
To eliminate the long time frame of generating transgenic plants, transient expression systems have been developed.
Women suffering from NCDs may have exhibited convoluted pathways of care seeking partly due to the long time frame of disease.
Given the long time frame of review, and the changing appreciation of disease itself by clinicians, we acknowledge the limitations this places on the study, and therefore highlight the descriptive data retrieved.
However, where the risk is lower, the long time frame of the development of many liver diseases means that GPs can continue to address modifiable liver disease risk factors (eg, alcohol misuse).
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Themes raised as barriers for current POCT included complexity, long time frames of the so-called "rapid" test, multiple time-driven steps, requiring laboratory technician, difficulty in reading result, interruption of workflow, unreliability, and invasiveness.
A detailed sensitivity analysis is not feasible because the model is expensive to simulate (particularly for the long time frames of Figure 9, for example), the number of parameters is large and would require calculation of 46x46 Fischer Information matrix (or cross-correlation matrix), and we do not have standard error estimates for all of the data used to identify the model.
Secondly, there is a need to use a long time frame to catch all the late effects of care.
Where studies have been undertaken to map the ultrastructure of whole organisms, they have required experienced electron microscopists working over long time frames to collect, image and analyse thousands of serial sections, as in the mapping of neural networks in Caenorrhabditis elegans [1].
Yearly parameters captured by the proposed approach allow for analysis of complex, non-linear trends over a long time frame, examination of characteristics of individual seasons, and assessment of inter-season heterogeneity and intra-season correlations.
"In a very long time frame — millions of years — it's guaranteed that at least some of them will still be there," he added.
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