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Thermogravimetric oxidation tests (TGA) were performed to examine the long term protection.
In addition, long term protection from joint degeneration has not yet been demonstrated (Wirth et al. [2002]).
This is no guarantee of long term protection.
Furthermore, the STMΔhfq also conferred long term protection against challenge.
This has been explained as long term protection as well as activity against surviving bacteria [13].
In addition it demonstrates that long term protection to filoviruses is achievable, and provides us with clues as to the correlates of immune protection.
Vaccines require optimal adjuvants and carrier molecules to achieve effective long term protection.
Vaccines require optimal adjuvants, including immunopotentiator and delivery systems, to offer long term protection from infectious diseases in animals.
However, the role of KALSOME™10 in prevention of reinfection after cure and long term protection from VL need further investigation.
Therefore, encapsulation of AmB in our formulation not only maintains the inherent immunomodulatory effects of AmB, but also enhances it, which is a prerequisite for long term protection.
This was interpreted to mean a single antigen might not be adequate to provide full and/or long term protection [ 14- 19].
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