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Second, independently of psychiatric diagnoses, childhood trauma induces long-term modifications in inflammation processes (Baumeister et al. 2015; Coelho et al. 2014; Tursich et al. 2014).
Stabilisation of these changes to produce long-term modifications in transmission requires protein synthesis that may take several hours [2], [12].
These long-term modifications in receptive field statistics match recent sensory perception experiments.
Long-term modifications in the chromatin may cause changes in gene expression and there by regulate many important cellular pathways.
This review attempts to probe beneath those functions and consider the cellular and molecular mechanisms through which NO evokes short- and long-term modifications in neural performance.
Dendritic calcium is responsible for triggering a variety of mechanisms of cellular plasticity that cause short- and long-term modifications in the strength of PC synapses (Gao et al., 2012).
Unified model of pre- and postsynaptically expressed STDP. (A ) The synaptic weight is the product of a presynaptic factor P and a postsynaptic factor q. Long-term modifications in P and q are governed by interactions between the pre- and postsynaptic spike trains.
The long-term modification in the weight is achieved by modifying the postsynaptic factor q and the presynaptic factor P. The postsynaptic factor is modified with every postsynaptic spike Y according to (6) Δ q = c + x + (t ) y − (t − ϵ ) Y (t ) ︸ Triplet post LTP, where c+ is a constant that sets the amount of postsynaptic LTP.
Mating causes extensive short- and long-term modifications of physiology and behavior in females.
"The long-term modifications of the estuaries because of the Clean Water Act have made all the difference," Mr. Mankiewicz said.
Our results bridge studies showing the role of the cholinergic system in selective attention (cholinergic reinforcement of visual stimuli) in V1 [1] and visual learning (long-term modification of synaptic responses and connections in V1) [12] [52], [52].
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