Exact(1)
With a CR rate of 73%%, an OS rate of 82 % and a PFS rate of 64%% these data confirm that MACOP-B is very effective in adult LCH, inducing long term complete responses in a significant fraction of patients.
Similar(59)
Because of its poor prognosis, it is likely that it might require more intensive treatment approaches, including allogeneic progenitor cell transplantation to achieve long-term complete remissions.
Although long-term complete remissions are rare, few reports describe cases after chemotherapy.
The primary goal of any therapy is to induce a long-term complete remission or cure.
Long-term, complete meteorologic data are available from the Tea Research Foundation.
Although long-term complete remissions are rare, some authors have reported cases after chemotherapy treatment [ 2- 6].
In contrast, in selected patients, the use of high doses of IL-2 has provided long-term complete remission (Rosenberg et al, 1994).
Efficacy of treatments in patients with alopecia totalis and alopecia universalis is poor, with long-term complete regrowth in less than 20% of patients.
Following chemotherapy treatment, TGF- β1 levels were significantly reduced, while patients in long-term complete remission had low exosomal TGF- β1 levels.
Fifty (66.7%) of 75 patients with WHO type A, AB and B1 thymomas achieved long-term complete remissions with primary complete resection alone.
Combined chemo-/immunotherapy has shown high objective response rates and a significant though small proportion of long-term complete responders in metastatic malignant melanoma.
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