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Bergstrom and Pritchart [24] suggested that long-term bottlenecks increase the selection pressure on deleterious mutations by increasing the variance in fitness among hosts.
Conversely, building upon the theory proposed by Lynch and Conery [6], Babenko et al. [38] suggested that intron gain/loss is not a commonly ongoing process, but rather may be triggered by certain dramatic evolutionary events that lead to long-term bottlenecks.
F was assessed for each K to search for bottlenecks in the long term.
Then, F for each cluster can be used as an indicator of genetic drift and/or bottleneck in the long term [ 44, 47].
d N/d S or Kr/Kc, on the other hand, are not expected to be strongly impacted by recent population bottlenecks but instead reflect variation in long term Ne.
An extreme change of allele frequency occurs due to population bottlenecks that dominate the process of random drift in the long term [ 39].
It's very long term.
Long term?
What about long term?
Long term, it.
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