Sentence examples for long term activation from inspiring English sources

Moreover, long term activation of YAP/TAZ may lead to tumorigenesis, thus caution should be taken when using YAP/TAZ activators in regenerative medicine.

We were interested in the long term activation of pERK, as it could be related to permanent activation of the TG.

The present study was designed to assess the metabolic effects in healthy mice of long term activation of the GIP receptor by N-AcGIP LysPAL37), N-AcGIP LysPAL37ting GIP receptor agonist.

These data indicate that long term activation of the GIP receptor by daily treatment with N-AcGIP LysPAL37) N-AcGIP LysPAL37 tolerance due to enhancement of pancreatimprovedcell glucose responsiveness and insulin secretolerance

Based on these previous findings we speculated that hypersensitivity and trigeminovascular activation could be maintained for a longer period of time (7 days) and that application of algesic substances onto the dura mater could be used as an animal model for long term activation of the trigeminovascular system.

These observations suggest that NK-4 promotes neurite-outgrowth in PC12 cells by reduction of ROS via induction and maintenance of long term activation of ERK1/2.

Long-term activation of MG through the secretion of active cytokines and molecules can increase the formation of age spots and the contents of the tau protein hyperphosphorylation, which promote the nerve tangles [ 9].

In contrast, long-term activation of cytokines seems to be detrimental: mice lacking the active forms of IL-1β and IL-18 (i.e. a caspase-1 knockout model) exhibited both improved peri-infarct survival and decreased ventricular dilatation after experimental MI, possibly due in part to a decrease in MMP-3 activity and reduction of apoptosis.

Thus, inhibition of long-term activation of the βCR may have therapeutic implications.

Large-scale production of clinical grade NK cells through long-term activation in ex vivo cultures are another novel means in achieving these goals.

Neutron-induced transmutation of materials in a D T fusion power plant will give rise to the potential for long-term activation.