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Predictions of long regions without regular secondary structure.
We find that S/MARs exhibit long regions of extensive destabilization.
In the third set, we added transient corruption on five randomly selected non-overlapping 1 min long regions.
In this experiment, we add artificial corruption to the last minute of the data and to 1 min long regions starting at the 2nd, 4th, or 6th minute.
To capture this important property in this model, glucose chain in each EF were assumed to pass through multiple crystalline regions (200 glucose molecules long regions) separated by amorphous regions.
The telomeres are long regions of repetitive noncoding DNA that cap chromosomes and undergo partial degradation each time a cell undergoes division (see Hayflick limit).
Does the ROSG model explain extremely long genes with many exons embedded between very long regions of introns?
IUPred and Ucon were previously established to be very accurate in the distinction between disordered and well-ordered long regions.
Interference might also be involved in the presence of long regions with low recombination activity in the middle third of each chromosome.
Our group identified long regions with no regular secondary structure (NORS), i.e. ≥70 sequence-consecutive surface residues depleted of helices and strands [55].
In contrast, only 13% of proteins from a set of proteins with well-defined ordered structures contain such long regions of predicted disorder [6].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com