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On the other hand methamphetamine's clearance from brain was very slow, which is likely to result in long lasting exposure of the brain to the sympathomimetic effects of this drug and contribute to its neurotoxicity.
CMD mainly results from a long lasting exposure to an unhealthy lifestyle.
Oral administration of NVP-BHG712 showed a long lasting exposure of parent compound in plasma as well as in different tissues (Fig. 3b).
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Stroke is considered as a disease which can be developed by long-lasting exposure to risk factors related to lifestyle.
Thus, despite the existence of rundown during long-lasting exposure of Halo-expressing neurons to yellow light, brief periods of blue light exposure will facilitate the optimal performance of Halo during long periods of neural inhibition in vivo.
This is undoubtedly true for short-term increases in PM, which are triggers for acute cardiovascular events [7], but probably also for long-lasting exposure to urban PM, which increases the risk of cardiovascular mortality and morbidity [4], [6], possibly by accelerating atherosclerosis [8] [10].
Stroke is regarded as one of the diseases developed by long-lasting exposure to risk factors associated with lifestyle.
Firstly, different occupational groups and amateur radio operators were considered as potential cohorts with high and long-lasting exposure to RF-EMF.
The main conclusion of the analysis is that short time periods are sufficient to re-obtain low MIC-values after long-lasting exposure to these antibiotics.
A major objective for the feasibility study was to investigate health effects in a group of persons in which a reasonable exposure assessment was feasible, and in which a potential for some high and long-lasting exposure was present.
Carcinoid heart disease (CHD) is a well-known complication of long-lasting exposure to high levels of serotonin (Tornebrandt et al, 1986; Lundin et al, 1988; Robiolio et al, 1995; Westberg et al, 2001; Zuetenhorst et al, 2003).
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