Neonatal treatment of rat pups with clomipramine (CLI) has been shown to cause long-lasting and persistent depression-related behaviors and changes in sleep architecture and in brain-derived neurotrophic factor (BDNF) signaling in adult animals, producing an animal model of depression.
Is it long-lasting and persistent even though the inflammatory phase is resolved?
Prolonged incubation of cerebellar neurons with cimes, which leads to the intracellular accumulation of the metabolically stable cimesP, induced long-lasting and persistent increases in the resting intracellular calcium ([Ca]i) which amounted up to 900 nM after 16 h of incubation.
Long lasting and wonderfully rich, it is elegantly mellow with a creamy, long-lasting taste.
The effect is dose dependent, long lasting and statistically significant.
Malar edema is long lasting and responds poorly to treatment.
Long-lasting and thorough.
These benefits are physiologically verified, long-lasting, and clinically meaningful.
The effect is dose-dependent, long-lasting, and specific.
They are long-lasting and colorful.
