Although the safety of long-term statin use has been generally established, concerns about the balance of risks and benefits of statins still exist for some medical professionals and patients, and issues concerning their side effects are occasionally widely publicised.
Because investors feel far less certain about the long-term prospects of these companies, their stock prices are much more sensitive to good or bad news than are those of larger, more established concerns.
These concerns appear to stem from more positivistic technocratic environments and mindsets that have been long established and protected within science [ 33], where decision-making is done by 'experts' and technical language is the accepted norm.
"This has been long established".
But this is a long established tendency.
He had long established ties with Al Qaeda".
This principle is well understood and long established.
"Those rules are intentional, long established and carefully considered.
Both tools are long established.
"I spent too long establishing that name," he said.
Catering is outstanding in many of the longest established academies.
