Too long confined to cameos, he has taken centre stage.
Because dengue was long confined to the tropics, it remains a little-understood disease.
The roots of the problem run deep in a conservative society that is having trouble adjusting to educational and economic advances by women, long confined to the home.
One reason for this is Japan's half-century history of one-party dominance, which has long confined the most important battles to within the LDP itself.
Long confined to the serious appreciation of high art and classical music, it is now applied to an endless cascade of pursuits.
And if you know anything about Williams's life, you will certainly think of his relationship with his sister, Rose, the defining love of his life and by then long confined to a mental institution.
Long confined to the elevated lines, where riders' thoughts on friends and co-workers often become topics for public consumption, the ability to chat could be a mixed blessing underground.
The extent of people's doubts about the Tories' values and motives explain why the party has been so long confined to the third of voters it can currently muster.
This baby had occurred almost by itself: it seemed to her to have arisen out of an abject mulch of flesh, out of bodies so long confined together that they spawned other bodies.
Ambassadors picked up what news they could, and sent the result off by horse and carriage; travellers added their titbits; but the organised collection of public information was a 19th-century arrival, and was anyway long confined to the prose of written journalism, not the vivid screen.
