Middle age has long been conceptualized as that phase of life where we cease thinking about our potential as human beings, and start focusing on our limitations.
RA has long been conceptualized as a chronic, even relentless, disease with changes (?epigenetic) in synoviocytes leading to joint destruction even in the absence of inflammation.
Traditionally, health was simply an absence of illness, but it has long been conceptualized through a more holistic definition that recognizes the importance of physical, psychological, social, and spiritual well-being (29, 30).
Although lupus nephritis has long been conceptualized as a classic immune complex disease, studies conducted in both human and murine systems have revolutionized the concept of immune complexes and have demonstrated convincingly that immune complexes can promote aberrant cytokine production, serving as potent inducers of IFN-α.
"The Widow Clicquot," Tilar J. Mazzeo's sweeping oenobiography of Barbe-Nicole Clicquot Ponsardin, is the story of a woman who was a smashing success long before anyone conceptualized the glass ceiling.
Case in point: Longplayer, a thousand years long musical composition conceptualized by Jem Finer in league with Artangel and Brian Eno, naturally, plus a whole collective of new agers.
This idea was developed further by Barnett and Whiteside who conceptualized the long-wave nature of HIV in the three curves depicted in Figure 1[ 2].
Through a spokesman, Mr. Capoccia said yesterday that he had been a financial backer of the mayor's campaigns since "long before this project was conceptualized".
Krasznahorkai spoke in English, a language he used lyrically, if not always comprehensibly, informing the enraptured audience that his famously long, convoluted sentences are completely conceptualized in his head before he writes them down, and offering the opinion that the full stop "doesn't belong to human beings, it belongs to God", which is why he doesn't much care for paragraph breaks.
The possible long-term exposure/expression relationships can be conceptualized in three generic models: latency, cumulative, and pathway.
