Moreover DS persons present peculiar haemato-logical abnormalities, that include abnormal platelet counts, macrocytosis, alterations in lymphocytes composition [ 17, 18] and higher susceptibility to develop leukemia, including rare forms like acute megakaryoblastic leukemia, and other hematopoietic disorders [ 19– 219.
An observational study did not detect any ophthalmo-logical abnormalities in the children born to women who used hydroxychloroquine or chloroquine for a mean of 7.2 months during pregnancy [ 16].
Of particular interest to us is the research on using high-level languages and their logical representation using nested abnormality theories (NATs)—a form of circumscription with blocks that make knowledge representation modular.
Treatment of the underlying pathophysiological abnormality seems logical, but the main pharmacotherapeutic options include acid suppression, prokinetic drugs, and antidepressants [ 6, 25- 27], all of which have limited effects.
Microcirculatory dysfunction is a central abnormality in shock and represents a logical and promising therapeutic target.
The skilled clinician identifies how abnormalities in specific anatomic structures contribute to motion loss and then formulates a logical treatment plan to target these structures.
Schizophrenia is a multi-symptom disorder characterised by abnormalities in various domains of mental functioning including hearing (auditory hallucinations), belief (delusions), logical thinking (thought disorder), motivation and emotion [ 1].
The next logical step is the assessment of whether the aluminum concentration is related to the key genomic abnormalities associated with breast carcinogenesis.
It recommended looking for fever and abnormalities in the spinal fluid, and double-checking records to see which diagnosis seemed more logical based on a donor's age and medical history — an infection or a stroke.
The abnormalities of serotonin metabolism which have been demonstrated in IBS-D make 5-HT3 antagonists a logical treatment.
The next logical step is the assessment of whether or not the aluminum concentration is related to the key genomic abnormalities associated with breast carcinogenesis, which is currently ongoing in our research laboratories.
