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Since the function h is nonlinear, the solution locus will be a curved surface.
The estimation on the locus will be compared with previous geophysical estimations (Kato et al. 2015; Maeda et al. 2015).
Further analysis of the PPP1R1B locus will be required to clarify the mechanisms regulating expression at the mRNA and protein levels.
In such cases, little if any mapping is required since the phenotype-causing mutant locus will be one of the few, if not only loci found to be mutated in both WGS datasets.
In this report, MRL mice homozygous for the lpr mutation will be referred to as "lpr" and MRL mice homozygous wild type at this locus will be referred to simply as "MRL".
It should be pointed out that (i) if the Venter genome contains two contiguous Alu elements (∼600 bp), while the human reference genome contains one Alu element (∼300 bp) at the orthologous locus, this locus will be assessed as a Venter genome insertion; and (ii) Alu-Alu recombination-mediated deletions (ARMDs) have been shown to occur frequently throughout primate evolution [16], [17].
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For all the outlier data, candidate loci will be annotated by gene ontology database and the functional categories enriched with candidate loci would be considered as potentially selected.
These identified loci will be useful for potential application for evolutionary, population genetic and chromosome linkage mapping research on pearl oyster.
Such pleiotropic gene loci will be very useful for understanding the homologous/homeologous relationships among QTL and designing an appropriate marker-assisted breeding programme including multi-trait selection in order to accumulate ("pyramide") favorable alleles at different genetic loci.
Quantitative or complex phenotypic traits refers to traits that are affected by many genes, and hence often (depending on the variation available in the population) many loci will be found for each complex trait.
Additionally, the transferable microsatellite loci will be potentially useful for future studies that focus on establishing the standard operating system of molecular identification for Gastrodia elata, a traditional Chinese medicine.
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