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There is a free Locus of Control test available on the Internet.
Although petal CHS was the only locus with differential expression, we looked for correlated expression of ABP loci to test for potential trans-acting regulatory elements.
The peak areas were extracted using GeneMapper software (Applied Biosystems) and the ratio of test locus to reference locus was calculated for each sample.
In addition to identifying sweeps at individual loci, a variety of test statistics for identifying recurrent beneficial fixations exist.
As SNPs in LD were excluded from the analysis in order to increase effciency, a Bonferroni correction could have been used 28 [ correcting for [(# of locus) – (# of locus)]/2 tests].
This is a reliable, valid and well used method of testing locus of control [ 44] and has been used on a psychiatric population [ 45]. ● Caregiver Burden Inventory (CBI) [ 46].
Single locus tests of association identified one significant single locus effect (Table 2a) in IL12B at SNP rs3212227 for the allelic test of association (p = 0.04).
Exact tests of linkage disequilibrium revealed 62 (68.1%) significant associations between pairs of loci out of 91 tests performed for the whole sample.
Single locus tests of association in The Gambia identified a significant allelic association at IL12B SNP rs11574790 (Table 2a) (p = 0.05).
Single locus tests of association in fetal data were not as strong as maternal data and were not statistically significant after adjusting for the effects of confounders (gravidity and smoking) with the exception of KL (rs522796).
The copy number of the test locus is then estimated from the ratio of test to reference products.
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