Sentence examples for locus making from inspiring English sources

The effect of DNA methylation was enhancing as well as preventing nucleosomal occupancy (for example at the chicken beta globin locus) making it necessary to examine nucleosomal position at the individual promoter level [8], [46].

The trend test gives small P-values at many loci correlated with a causal locus, making it difficult to localize the causal locus.

S. Typhi BRD948 is a well-characterized laboratory S. Typhi strain, with the attenuating mutations in the aro locus making it auxotrophic for aromatic compounds.

For instance, expression of receptor-type tyrosine-protein phosphatase O Ptproo) is decreased in all three mutants and has direct binding of Wt1 to its genomic locus, making it a strong candidate for direct control by Wt1.

The gene segregating with the presence of the γ-D volatile has been shown to segregate as a single dominant locus, making it a prime candidate for the approach outlined in Additional file 1: Figure S1.

The two most predictive markers in field populations (CRW1683 and CRW1862) fall near the center and left side of the resistance locus, making it less likely that the causal alleles fall at a position greater than about 128 cM on the genetic map.

The feature of the complex organization of highly sequence-related homologues at the Pi2/9 locus makes it difficult to develop gene-specific molecular markers for the diagnosis and identification of known and novel alleles from diverse germplasm.

The high genetic variability at CYP21A2 locus makes the characterization of 21OHD alleles difficult, and, hence, complicates disease carrier detection and genetic counseling.

In this context, the location of RTN4R within the replicated and highly penetrant 22q11.2 schizophrenia susceptibility locus makes the gene a prime candidate for influencing disease susceptibility.

Several features of the ELN locus make it noteworthy.

Recombination events, which took place at this locus, make the construction of a bifurcating tree less relevant.