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The locus is occupied by a gene that encodes a protein similar to the N-terminal region of McrB in most H. pylori strains.
An uppercase character represents a dominant gene, a lowercase character represents a recessive gene; no character in a gene pair implies that it is not relevant for the genotype if the locus is occupied by a dominant or recessive gene.
The DFNA28 (OMIM: 608641) locus is occupied by the GRHL2 (grainyhead like 2) gene, which is also known as TFCP2L3 (transcription factor cellular promoter 2-like 3) or BOM (brother of mammalian grainyhead), and is a widely expressed transcription factor in human epithelial tissues [ 11].
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Accordingly these ISRE loci are occupied by an average of only 18.1 ChIP-seq tags, whereas the remaining 30 loci containing GAS exhibit an average of 311.9 tags.
The Ty1 pattern is characterized by a low level of polymorphism between individuals because almost all the same loci are occupied in many strains.
Of these, more than 6700 target loci are occupied by CREM in testis, yet the expression of only a small subset of these genes are affected upon CREM knock out.
We previously identified a region located ∼10 kb upstream of the ttk locus that is occupied by multiple mesoderm-specific regulators (Zinzen et al., 2009) (Fig. 1A).
The genome size of the fugu fish is 4 × 108 bp and 1/3 of it is occupied by gene loci [ 16].
So where you expect a family whose home is occupied by thugs to fight back and exact vengeance - the locus classicus being William Wyler's The Desperate Hours - you get, instead, In Cold Blood, where the householders are brutally murdered and the killers get away.
In contrast, compact factors will be preferentially shared between proximal loci, and therefore the probability of a locus to be occupied by a compact explorer is a function of the occupation history of its neighboring sites: it is distance and time dependent.
Our data identify 9037 binding loci that are occupied in either a common or cell-specific manner.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com