Sentence examples for locus control from inspiring English sources

LCR, locus control region.

Development and homeostasis require coordinate regulation of neighbouring genes through a process termed locus control.

Some locus control elements and enhancers transcribe lincRNAs, hinting at possible roles in long-range control.

Numerous locus control region (LCR) activities have been discovered in gene loci important to immune cell development and function.

Surprisingly, the β-globin locus control region (LCR), although critical for high-level gene expression, plays little role in the overall architecture of the active locus.

This method is used to show that the distal β-globin locus control region is intimately associated with an actively transcribed β-globin gene in erythroid cells.

We produced a second HD-Ad5/35 vector expressing a TALEN targeting the DNase hypersensitivity region 2 (HS2) within the globin locus control region.

In erythroid cells, the locus control region (LCR) and β-globin promoter form a chromatin loop that requires transcription factor GATA1 and the associated molecule Ldb1.

A conserved regulatory element, the locus control region (LCR), was revealed by analyzing DNase I hypersensitive sites, H3K4 trimethylation marks and GATA1 binding sites.

(2016) reported massive multi-layer genome reorganization from naive B cells to germinal center B cells, centered on a locus control region of Bcl6.

We applied this method in an analysis of the chromatin structure of the previously described mouse β-globin locus control region (LCR) using fetal liver cells.