To summarize, despite significant but different effects of balancing selection acting on HLA−A, −B and −DRB1, similar conclusions are drawn for these three HLA loci concerning the likelihood of the different scenarios tested, suggesting that demography shaped the observed genetic patterns to a greater extent than did selection.
In type 2 diabetes many of the loci encode proteins concerned with insulin secretion rather than insulin signalling, which had previously been the focus of research.
Our first aim concerned the locus of compensatory mechanisms.
Data quality analyses indicated only minor issues concerning locus scoring accuracy, nonrandom association of loci, and population admixture.
The way in which dominance is established is perhaps the most important locus of disagreement concerning Kuhn's work.
A recent study suggested that the locus of plasticity concerning glutamatergic synapses may depend on the time in vitro, not on the actual age of the tissue[43].
Although mtDNA is a single locus, some parallels concerning the African expansion of M1 and U6 can be drawn from autosomal data.
The questions were to capture respondents' perceptions about the scientific evidence, safety, effectiveness, and holistic aspects of complementary therapies, as well as items concerning locus of control and how decisions are made to use or not use complementary therapies.
Psychological factors: perceived locus of control concerning their own health (a lot, no or hardly); perceived health status (good, poor); fear of giving birth (not so anxious, anxious,); fear of bearing a handicapped child (not so anxious, anxious); pregnancy-related concerns about their appearance (not so anxious, anxious,).
The annotation of genes whereby repeat sequences are shown to be part of an open reading frame can help define genetic loci better and/or raise questions concerning the locus.
