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We integrated the vgb gene from Vitreoscilla sp. into the genome at the pyrA locus behind the strong gpdA promoter from Aspergillus nidulans.
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However, in 2007, Barsh and his colleagues determined that the loss of three letters of genetic code in another gene, called the K locus, was behind the black fur of Labrador retrievers, great Danes, German shepherds, and dozens of other breeds.
In these mice we had used gene targeting in ES cells to introduce a stop codon into exon 16 of the endogenous mouse APP locus just behind the α-secretase cleavage site.
[T]he feeling of being a subject inside your head, a locus of consciousness behind your eyes, a thinker in addition to the flow of thoughts [is not real].
That is, while he first construed knowledge on the model of self-awareness in which self reflects itself within itself, he also felt compelled to find a locus of non-differentiation behind the distinction between such awareness and things seen from its vantage point.
For inducible expression from the AAVS1 locus, dCas9-VPR was placed behind a TRE promoter in the AAVS1 homologous recombineering donor plasmid, as shown in Fig. S2A.
Not only may gene gene interaction and genetic background play a role, but also noncoding variants or mutations in nearby loci may be behind most of the 6p12-p11-linked JME cases.
A policy that looks like an appeal to one group is actually an appeal to another — the locus classicus being Bush's promise to "leave no child behind" in education, which gestures, not disingenuously, toward ghetto kids but drives up Bush's poll numbers with suburban women.
Gene deletion by HR between the loxP sites results in marker removal, leaving behind a single repeat at the deleted gene locus.
Upon expression in the mutated strains of tnpR, the transposon γδ resolvase gene, res-ΩKm-res, was excised efficiently leaving behind a single res sequence at the mutated locus.
In France (but also, in more subtle ways, in other contexts) the secular is portrayed as an aseptic meeting place: a locus that you enter by leaving cultural and religious rules behind.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com