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2) Furthermore, its impact on quality of life is substantial due to an impairment of locomotor function and decrease in functional capacities.
We conclude that although the observable functional phenotypes such as locomotor function and sleep are comparable, the mechanisms utilized by different TDP-43 variants in different tissues (e.g. motor neurons versus glia) might be divergent at the cellular level.
One week after acupuncture at JiaJi acupoint, the locomotor function and infarct volumes were tested.
For example, in the SCI model, treatment with NgR1-Fc may lead to a significant recovery in locomotor function and increased the growth of axons11.
RAGE antibody microinjection does not improve locomotor function and the BBB score exhibits no significance compared with the SCI vehicle group from 1 week to 4 weeks after SCI (Fig. 9).
Three groups (n = 72) of 30-day-old male Sprague Dawley rats were spinally hemisected at T13 and allowed 4 weeks for adequate recovery of locomotor function and development of allodynia and hyperalgesia.
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In this conceptual review, we highlight our strategy for, and progress in the development of corticospinal neuroprostheses for restoring locomotor functions and promoting neural repair after thoracic spinal cord injury in experimental animal models.
A sound understanding of how diverse functions are implemented in a simple foot segment during human locomotion might be useful to gain insight into the overall foot locomotor functions and hence to facilitate clinical diagnosis, rehabilitation product design and humanoid robot development.
However, while a dramatic improvement in the locomotor functions and learning of motor skills was observed in Ts65Dn mice from both post-weaning and adult cohorts, improved object memory was seen only in Ts65Dn mice that had free access to the wheel from weaning.
Adequate maintenance of muscle mass throughout life is important to preserve locomotor functions and diminish the risk of falling.
Aging-related Parkinsonism presents symptoms similar to Parkinson's disease (PD) and, like PD, they are progressive, impair performance of essential locomotor functions, and increase risk of cognitive impairment, dementia, and death [2] [5].
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