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In the first stage, if the locomotor activity level was over threshold then an active wake state was assigned.
If appropriate methods of analysis are used that take into account sleep and locomotor activity level, mice are a good model for understanding the contribution of circadian timing to cardiovascular function.
The red/white and left/right choice, alternation pattern (i.e., number of entries into an opposite arm of the maze during consecutive trials) and locomotor activity level at several zones of the maze was documented.
Of note, the nigral DA value in the outlier subject of the older group was at the 12-month mean (8.3 ng/mg protein) and this subject had the highest locomotor activity level of the group.
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When the temperature was raised to 30°C, above the temperature required for TrpA1 activation, TH/TrpA1 flies increased locomotor activity levels, whereas control flies did not (Fig. 2H,I).
Susceptibility to this ethanol effect varies as a function of baseline locomotor activity levels.
The results from these studies (Figures 4b d) showed that the administration of AM404 had little effect on shock reactivity or overall locomotor activity levels in the testing chamber (p>0.5 for both comparisons).
However, concerns exist regarding confounds like stress, increased locomotor activity levels, and decreased motivation to perform operant tasks induced by the methods employed.
We here propose a novel procedure for sleep deprivation in rats and evaluate how it affects sleep, corticosterone concentration profiles, locomotor activity levels, and motivation to perform an operant task.
We first evaluated normal locomotor activity levels in animals with reduced and wild-type AMPK.
However, adult mice showed a significant 12% increase in locomotor activity levels compared to adolescent subjects (age, U = 131.0, P<0.0131.0,
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