Transcription factor (TF -DNA binding loci are explored by analyzing massive daTF -DNAgenerated with application of Chromatin Immuno-Precipitation (ChIP)-bindingigh-throughput sequencing technolocies.
Finally, the influence of linkage on the degree of local adaptation, the migration load, and the effective migration rate at a neutral locus is explored.
The likelihood surface of each locus was explored stepwise along axes for both center position (c) and width (w) while allowing other parameters to vary at each point [ 50].
The evolutionary properties of the four-locus genotype-phenotype map were explored using computer simulations.
Allele frequencies were explored in different population groups for both the Y locus and the homologous locus in the X chromosome showing a similar allele distribution pattern in the X and Y homologous loci.
Plausible interactions were explored.
A large number of identified susceptibility loci have been explored in both CD and UC [ 2].
By the mid-nineties, linkage studies had proven to be a robust means of identifying highly penetrant loci underlying monogenic disease such as cystic fibrosis [10] and Huntington's disease [11] and the utility of the method for mapping complex disease loci was increasingly being explored.
